SB431542

Product Specifications

CAS Number

301836-41-9

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

C1OC2=C (O1) C=C (C=C2) C3=C (NC (=N3) C4=CC=C (C=C4) C (=O) N) C5=CC=CC=N5

Molecular Formula

C22H16N4O3

Additionnal Information

SB431542 is a potent and selective inhibitor of ALK5 with IC50 of 94 nM in a cell-free assay, 100-fold more selective for ALK5 than p38 MAPK and other kinases.

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