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Masitinib

Product Specifications

CAS Number

790299-79-5

Synonyms

AB1010

Target

C-Kit

Applications

Protein Tyrosine Kinase

Smiles

CC1=C (C=C (C=C1) NC (=O) C2=CC=C (C=C2) CN3CCN (CC3) C) NC4=NC (=CS4) C5=CN=CC=C5

Molecular Formula

C28H30N6OS

Additionnal Information

Masitinib is a novel inhibitor for Kit (c-Kit) and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms. Phase 3.

Storage Conditions

2 years -80 in solvent

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