What is the catalog number for Olaparib (AZD2281)?

The catalog number for Olaparib (AZD2281) is C07481-10mM/1mL.

What sizes are available for Olaparib (AZD2281)?

Olaparib (AZD2281) is available in the following size(s): 10 mM/1mL.

Is Olaparib (AZD2281) in stock?

Olaparib (AZD2281) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Olaparib (AZD2281)?

Olaparib (AZD2281) is requires dry ice shipping.

Olaparib (AZD2281)

Product Specifications

CAS Number

763113-22-0

Synonyms

Ku-0059436

Target

PARP

Applications

DNA Damage/DNA Repair

Smiles

C1CC1C (=O) N2CCN (CC2) C (=O) C3=C (C=CC (=C3) CC4=NNC (=O) C5=CC=CC=C54) F

Molecular Formula

C24H23FN4O3

Additionnal Information

Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.