Elesclomol (STA-4783)
Product Specifications
CAS Number
488832-69-5
Target
HSP (HSP90)
Applications
Cytoskeletal Signaling
Smiles
CN (C (=S) C1=CC=CC=C1) NC (=O) CC (=O) NN (C) C (=S) C2=CC=CC=C2
Molecular Formula
C19H20N4O2S2
Additionnal Information
Elesclomol (STA-4783) is a novel potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells. Phase 3.Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand and inhibits FDX1-mediated Fe-S cluster biosynthesis.Elesclomol (STA-4783) is a potent copper ionophore and can be used in the research of copper-dependent cell death (cuproptosis) .
Storage Conditions
2 years -80 in solvent
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