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Elesclomol (STA-4783)

Product Specifications

CAS Number

488832-69-5

Target

HSP (HSP90)

Applications

Cytoskeletal Signaling

Smiles

CN (C (=S) C1=CC=CC=C1) NC (=O) CC (=O) NN (C) C (=S) C2=CC=CC=C2

Molecular Formula

C19H20N4O2S2

Additionnal Information

Elesclomol (STA-4783) is a novel potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells. Phase 3.Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand and inhibits FDX1-mediated Fe-S cluster biosynthesis.Elesclomol (STA-4783) is a potent copper ionophore and can be used in the research of copper-dependent cell death (cuproptosis) .

Storage Conditions

2 years -80 in solvent

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