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Temsirolimus

Product Specifications

CAS Number

162635-04-3

Synonyms

NSC 683864, CCI-779

Target

MTOR

Applications

PI3K/Akt/mTOR

Smiles

CC1CCC2CC (C (=CC=CC=CC (CC (C (=O) C (C (C (=CC (C (=O) CC (OC (=O) C3CCCCN3C (=O) C (=O) C1 (O2) O) C (C) CC4CCC (C (C4) OC) OC (=O) C (C) (CO) CO) C) C) O) OC) C) C) C) OC

Molecular Formula

C56H87NO16

Additionnal Information

Temsirolimus is a specific mTOR inhibitor with IC50 of 1.76 μM in a cell-free assay. Temsirolimus induces autophagy and apoptosis.

Storage Conditions

2 years -80 in solvent

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