Tandutinib (MLN518)
Product Specifications
CAS Number
387867-13-2
Synonyms
CT 53518, NSC726292, MLN518
Target
FLT3
Applications
Protein Tyrosine Kinase
Smiles
CC (C) OC1=CC=C (C=C1) NC (=O) N2CCN (CC2) C3=NC=NC4=CC (=C (C=C43) OC) OCCCN5CCCCC5
Molecular Formula
C31H42N6O4
Additionnal Information
Tandutinib (MLN518, CT53518, NSC726292) is a potent FLT3 antagonist with IC50 of 0.22 μM, also inhibits PDGFR and c-Kit, 15 to 20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 2.
Storage Conditions
2 years -80 in solvent
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