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Mirdametinib (PD0325901)

Product Specifications

CAS Number

391210-10-9

Target

MEK

Applications

Protein Tyrosine Kinase

Smiles

C1=CC (=C (C=C1I) F) NC2=C (C=CC (=C2F) F) C (=O) NOCC (CO) O

Molecular Formula

C16H14F3IN2O4

Additionnal Information

Mirdametinib (PD0325901) is a selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM in cell-free assays, roughly 500-fold more potent than CI-1040 on phosphorylation of ERK1 and ERK2. Phase 2.

Storage Conditions

2 years -80 in solvent

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