Mirdametinib (PD0325901)
Product Specifications
CAS Number
391210-10-9
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
C1=CC (=C (C=C1I) F) NC2=C (C=CC (=C2F) F) C (=O) NOCC (CO) O
Molecular Formula
C16H14F3IN2O4
Additionnal Information
Mirdametinib (PD0325901) is a selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM in cell-free assays, roughly 500-fold more potent than CI-1040 on phosphorylation of ERK1 and ERK2. Phase 2.
Storage Conditions
2 years -80 in solvent
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