Nilotinib
Product Specifications
CAS Number
641571-10-0
Synonyms
AMN-107
Target
Bcr-Abl
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=C (C=C1) C (=O) NC2=CC (=CC (=C2) C (F) (F) F) N3C=C (N=C3) C) NC4=NC=CC (=N4) C5=CN=CC=C5
Molecular Formula
C28H22F3N7O
Additionnal Information
Nilotinib is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.
Storage Conditions
2 years -80 in solvent
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