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Panobinostat (LBH589)

Product Specifications

CAS Number

404950-80-7

Synonyms

NVP-LBH589

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

CC1=C (C2=CC=CC=C2N1) CCNCC3=CC=C (C=C3) C=CC (=O) NO

Molecular Formula

C21H23N3O2

Additionnal Information

Panobinostat (LBH589, NVP-LBH589) is a novel broad-spectrum HDAC inhibitor with IC50 of 5 nM in a cell-free assay. Panobinostat (LBH589) induces autophagy and apoptosis. Panobinostat effectively disrupts HIV latency in vivo. Phase 3.

Storage Conditions

2 years -80 in solvent

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