FL-411
Product Specifications
CAS Number
2118944-88-8
Synonyms
BRD4-IN-1
Target
Autophagy
Applications
Autophagy
Smiles
CC1=CC (=CC (=C1O) C) C2=NC3=C (C4=C (S3) CN (CC4) C) C (=O) N2
Molecular Formula
C18H19N3O2S
Additionnal Information
FL-411 (BRD4-IN-1) is a potent and selective inhibitor of Bromodomain-containing protein 4 (BRD4) with IC50 of 0.43 μM for BRD4 (1) . FL-411 induces ATG5-dependent autophagy-associated cell death (ACD) by blocking BRD4-AMPK interaction.
Storage Conditions
3 years -20°C powder
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