What is the catalog number for Gefitinib?

The catalog number for Gefitinib is C07446-100mg.

What sizes are available for Gefitinib?

Gefitinib is available in the following size(s): 100 mg.

Is Gefitinib in stock?

Gefitinib is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Gefitinib?

Gefitinib is requires dry ice shipping.

Gefitinib

Product Specifications

CAS Number

184475-35-2

Synonyms

ZD1839

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

COC1=C (C=C2C (=C1) N=CN=C2NC3=CC (=C (C=C3) F) Cl) OCCCN4CCOCC4

Molecular Formula

C22H24ClFN4O3

Additionnal Information

Gefitinib is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively. Gefitinib promotes autophagy and apoptosis of lung cancer cells via blockade of the PI3K/AKT/mTOR pathway.