Dasatinib
Product Specifications
CAS Number
302962-49-8
Synonyms
BMS-354825
Target
Bcr-Abl
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C (=CC=C1) Cl) NC (=O) C2=CN=C (S2) NC3=CC (=NC (=N3) C) N4CCN (CC4) CCO
Molecular Formula
C22H26ClN7O2S
Additionnal Information
Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.
Storage Conditions
2 years -80 in solvent
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