PD184352 (CI-1040)
Product Specifications
CAS Number
212631-79-3
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
C1CC1CONC (=O) C2=C (C (=C (C=C2) F) F) NC3=C (C=C (C=C3) I) Cl
Molecular Formula
C17H14ClF2IN2O2
Additionnal Information
PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. PD184352 (CI-1040) selectively induces apoptosis.
Storage Conditions
2 years -80 in solvent
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View Details 224393-02 100 µL
Na+ CP (Sodium Channel Protein Type 9 Subunit alpha, Neuroendocrine sodium Channel, hNE-Na, Peripheral sodium Channel 1, PN1, Sodium Channel Protein Type IX Subunit alpha, Voltage-Gated sodium Channel Subunit alpha Nav1.7, SCN9A, NENA) discontinued
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