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Canertinib (CI-1033)

Product Specifications

CAS Number

267243-28-7

Synonyms

PD183805

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

C=CC (=O) NC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=C (C=C3) F) Cl) OCCCN4CCOCC4

Molecular Formula

C24H25ClFN5O3

Additionnal Information

Canertinib (CI-1033, PD183805) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3.

Storage Conditions

2 years -80 in solvent

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