Canertinib (CI-1033)
Product Specifications
CAS Number
267243-28-7
Synonyms
PD183805
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
C=CC (=O) NC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=C (C=C3) F) Cl) OCCCN4CCOCC4
Molecular Formula
C24H25ClFN5O3
Additionnal Information
Canertinib (CI-1033, PD183805) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3.
Storage Conditions
2 years -80 in solvent
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