What is the catalog number for Dovitinib (TKI-258)?

The catalog number for Dovitinib (TKI-258) is C07439-10mM/1mL.

What sizes are available for Dovitinib (TKI-258)?

Dovitinib (TKI-258) is available in the following size(s): 10 mM/1mL.

Is Dovitinib (TKI-258) in stock?

Dovitinib (TKI-258) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Dovitinib (TKI-258)?

Dovitinib (TKI-258) is requires dry ice shipping.

Dovitinib (TKI-258)

Product Specifications

CAS Number

405169-16-6

Synonyms

CHIR-258

Target

C-Kit

Applications

Protein Tyrosine Kinase

Smiles

CN1CCN (CC1) C2=CC3=C (C=C2) N=C (N3) C4=C (C5=C (C=CC=C5F) NC4=O) N

Molecular Formula

C21H21FN6O

Additionnal Information

Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays. Phase 4.