Thalidomide-OH
Product Specifications
CAS Number
5054-59-1
Synonyms
Cereblon ligand 2, E3 ligase Ligand 2
Target
E3 Ligase
Applications
Ubiquitin
Smiles
C1CC (=O) NC (=O) C1N2C (=O) C3=C (C2=O) C (=CC=C3) O
Molecular Formula
C13H10N2O5
Additionnal Information
Thalidomide-OH (Cereblon ligand 2, E3 ligase Ligand 2) is a presumed hydroxylated thalidomide metabolite, with weak antiangiogenic activity (the average inhibition rate of vessel density was 14% in 100 μg), also can be applicable to the recruitment of CRBN protein.
Storage Conditions
3 years -20°C powder
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