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BMS-536924

Product Specifications

CAS Number

468740-43-4

Synonyms

CS-0117

Target

IGF-1R

Applications

Protein Tyrosine Kinase

Smiles

CC1=CC (=CC2=C1N=C (N2) C3=C (C=CNC3=O) NCC (C4=CC (=CC=C4) Cl) O) N5CCOCC5

Molecular Formula

C25H26ClN5O3

Additionnal Information

BMS-536924 (CS-0117) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2.

Storage Conditions

2 years -80 in solvent

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