Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Afatinib

Product Specifications

CAS Number

850140-72-6

Synonyms

BIBW2992

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

CN (C) CC=CC (=O) NC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=C (C=C3) F) Cl) OC4CCOC4

Molecular Formula

C24H25ClFN5O3

Additionnal Information

Afatinib inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy.

Storage Conditions

2 years -80 in solvent

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

MMP2 Rabbit Polyclonal Antibody (APC-Cy5.5)
orb1594764 100 µL

MMP2 Rabbit Polyclonal Antibody (APC-Cy5.5)

Sign In for Pricing
View Details
Rabbit Polyclonal p14ARF/CDKN2A Antibody [DyLight 755]
NB200-159IR 0.1 mL

Rabbit Polyclonal p14ARF/CDKN2A Antibody [DyLight 755]

Sign In for Pricing
View Details
GOLPH3 (NM_022130) Human Recombinant Protein
E45H38481M5 20 µg

GOLPH3 (NM_022130) Human Recombinant Protein

Sign In for Pricing
View Details
1- (4-Methoxyphenyl) cycloheptan-1-amine hydrochloride
QZB52815-01 50 mg

1- (4-Methoxyphenyl) cycloheptan-1-amine hydrochloride

Sign In for Pricing
View Details
1- (4-Methoxyphenyl) cycloheptan-1-amine hydrochloride
QZB52815-02 0.5 g

1- (4-Methoxyphenyl) cycloheptan-1-amine hydrochloride

Sign In for Pricing
View Details
HX-375-2-YL-2 Pre-sized Sleeves for Printers
117035 2000 Roll (2000 Sleeve (s) x 1 Roll)

HX-375-2-YL-2 Pre-sized Sleeves for Printers

Sign In for Pricing
View Details