Nintedanib (BIBF 1120)
Product Specifications
CAS Number
656247-17-5
Synonyms
BIBF 1120, Intedanib
Target
FGFR
Applications
Protein Tyrosine Kinase
Smiles
CN1CCN (CC1) CC (=O) N (C) C2=CC=C (C=C2) N=C (C3=CC=CC=C3) C4=C (NC5=C4C=CC (=C5) C (=O) OC) O
Molecular Formula
C31H33N5O4
Additionnal Information
Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.
Storage Conditions
2 years -80 in solvent
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