What is the catalog number for Dactolisib (BEZ235)?

The catalog number for Dactolisib (BEZ235) is C16055-100mg.

What sizes are available for Dactolisib (BEZ235)?

Dactolisib (BEZ235) is available in the following size(s): 100 mg.

Is Dactolisib (BEZ235) in stock?

Dactolisib (BEZ235) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Dactolisib (BEZ235)?

Dactolisib (BEZ235) is requires dry ice shipping.

Dactolisib (BEZ235)

Product Specifications

CAS Number

915019-65-7

Synonyms

NVP-BEZ235

Target

ATM/ATR

Applications

PI3K/Akt/mTOR

Smiles

CC (C) (C#N) C1=CC=C (C=C1) N2C3=C4C=C (C=CC4=NC=C3N (C2=O) C) C5=CC6=CC=CC=C6N=C5

Molecular Formula

C30H23N5O

Additionnal Information

Dactolisib (BEZ235, NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR (p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits ATR with IC50 of 21 nM in 3T3TopBP1-ER cell. Dactolisib induces autophagy and suppresses HIV-1 replication. Phase 2.