Axitinib
Product Specifications
CAS Number
319460-85-0
Synonyms
AG 013736
Target
C-Kit
Applications
Protein Tyrosine Kinase
Smiles
CNC (=O) C1=CC=CC=C1SC2=CC3=C (C=C2) C (=NN3) C=CC4=CC=CC=N4
Molecular Formula
C22H18N4OS
Additionnal Information
Axitinib is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.
Storage Conditions
2 years -80 in solvent
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