Veliparib (ABT-888)
Product Specifications
CAS Number
912444-00-9
Synonyms
NSC 737664
Target
PARP
Applications
DNA Damage/DNA Repair
Smiles
CC1 (CCCN1) C2=NC3=C (C=CC=C3N2) C (=O) N
Molecular Formula
C13H16N4O
Additionnal Information
Veliparib (ABT-888, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2. Veliparib increases autophagy and apoptosis. Phase 3.
Storage Conditions
2 years -80 in solvent
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