Linifanib (ABT-869)
Product Specifications
CAS Number
796967-16-3
Synonyms
AL39324, RG3635
Target
CSF-1R
Applications
Protein Tyrosine Kinase
Smiles
CC1=CC (=C (C=C1) F) NC (=O) NC2=CC=C (C=C2) C3=C4C (=CC=C3) NN=C4N
Molecular Formula
C21H18FN5O
Additionnal Information
Linifanib (ABT-869, AL39324, RG3635) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, Flt-1/3 and PDGFRβ with IC50 of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3) . Linifanib (ABT-869) induces autophagy and apoptosis. Phase 3.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![THTPA Mouse Monoclonal Antibody [Clone ID: OTI4C11]](https://cdn.genprice.uk/products/937/68dd18b9061270361e907e71/imageurl/cf806180.webp)
CF806180 100 µg
THTPA Mouse Monoclonal Antibody [Clone ID: OTI4C11]
Sign In for Pricing
View Details ![ZNF286 (ZNF286A) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3C5]](https://cdn.genprice.uk/products/937/68dd1b7a061270361ea1bc02/imageurl/ta803404am.webp)
TA803404AM 100 µL
ZNF286 (ZNF286A) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3C5]
Sign In for Pricing
View Details 
![APOBEC4 Mouse Monoclonal Antibody [Clone ID: OTI3F11]](https://cdn.genprice.uk/products/937/68dd18bb061270361e908963/imageurl/cf810779.webp)
CF810779 100 µg
APOBEC4 Mouse Monoclonal Antibody [Clone ID: OTI3F11]
Sign In for Pricing
View Details