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MYCMI-6

Product Specifications

CAS Number

681282-09-7

Synonyms

NSC354961

Target

Myc

Applications

Apoptosis

Smiles

CCOC1=CC2=C (C3=C (C=C (C=C3) N=NC4=C (N=C (C=C4) N) N) N=C2C=C1) N

Molecular Formula

C20H19N7O

Additionnal Information

MYCMI-6 (NSC354961) is a potent and selective endogenous inhibitor of MYC:MAX protein interactions. MYCMI-6 blocks MYC-driven transcription and binds to the MYC bHLHZip domain with Kd of 1.6 μM. MYCMI-6 inhibits tumor cell growth in a MYC-dependent manner with IC50 of <0.5 μM. MYCMI-6 induces apoptosis.

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