γ-Mangostin
Product Specifications
CAS Number
31271-07-5
Synonyms
Gamma-Mangostin
Target
5-HT Receptor
Applications
Neuronal Signaling
Smiles
CC (=CCC1=C (C2=C (C=C1O) OC3=C (C2=O) C (=C (C (=C3) O) O) CC=C (C) C) O) C
Molecular Formula
C23H24O6
Additionnal Information
γ-Mangostin (Gamma-Mangostin) is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptors antagonist, which can reduce the perfusion pressure response of rat coronary artery to 5-HT2A with an IC50 of 0.32 μM and inhibit [3H] spiperone binding to cultured rat aortic myocytes with an IC50 of 3.5 nM. Gamma-Mangostin is also an inhibitor of Transthyretin (TTR) fibrillization.
Storage Conditions
3 years -20°C powder
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