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TC-E 5003

Product Specifications

CAS Number

17328-16-4

Synonyms

NSC 30176

Target

PRMT

Applications

Epigenetics

Smiles

ClCC (=O) NC1=CC=C (C=C1) [S] (=O) (=O) C2=CC=C (NC (=O) CCl) C=C2

Molecular Formula

C16H14Cl2N2O4S

Additionnal Information

TC-E 5003 (NSC 30176, Compound 2e) is a selective inhibitor of protein arginine methyltransferase 1 (PRMT1) with IC50 of 1.5 μM. TC-E 5003 modulates the lipopolysaccharide (LPS) -induced AP-1 and NF-κB signaling pathways and can possibly be further developed as an anti-inflammatory compound.

Storage Conditions

3 years -20°C powder

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