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TMN355

Product Specifications

CAS Number

1186372-20-2

Target

Immunology & Inflammation related

Applications

Immunology & Inflammation

Smiles

C1=CC=C2C (=C1) C (C3=CC=CC=C32) NC (=O) NC (=O) C4=C (C=CC=C4Cl) F

Molecular Formula

C21H14ClFN2O2

Additionnal Information

TMN355 (Compound 3i) is a potent inhibitor of cyclophilin A (CypA) with IC50 of 1.52 nM and reduces foam cell formation and cytokine secretion. TMN355 is used for the treatment of atherosclerosis.

Storage Conditions

3 years -20°C powder

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