TH1020
Product Specifications
CAS Number
1841460-82-9
Target
Others
Applications
Others
Smiles
C12=NC=NC (SC3=NN=C (N3CC4=CC=CC=C4) C5=CC=NC=C5) =C1SC6=NC=CC=C62
Molecular Formula
C23H15N7S2
Additionnal Information
TH1020 is a potent and selective toll-like receptor 5 (TLR5) /flagellin complex antagonist, with an IC50 value of 0.85 μM. TH1020 inhibits downstream signaling pathways activated by the TLR5/Flagellin complex. TH1020 is inactive against TLR2, TLR3, TLR4, TLR7 and TLR8.
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