RP-64477
Product Specifications
CAS Number
135239-65-5
Target
Acyltransferase
Applications
Metabolism
Smiles
CCCCCCCCCCOC1=CC=C (C=C1) C (=O) NC2=C (C=CC (=C2) C (=O) NCCCC) SC
Molecular Formula
C29H42N2O3S
Additionnal Information
RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) . RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively.
Storage Conditions
3 years -20°C powder
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