Oncrasin-1
Product Specifications
CAS Number
75629-57-1
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
C1=CC=C2C (=C1) C (=CN2CC3=CC=C (C=C3) Cl) C=O
Molecular Formula
C16H12ClNO
Additionnal Information
Oncrasin-1 (Onc-1) is a potent RNA polymerase II inhibitor with antitumor activity that kills various human lung cancer cells with K-Ras mutations. Oncrasin-1 drives abnormal aggregation of protein kinase C iota (PKCι) in nucleus of sensitive cells but not in resistant cells.
Storage Conditions
3 years -20°C powder
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