GFB-8438
Product Specifications
CAS Number
2304549-73-1
Target
TRP Channel
Applications
Neuronal Signaling
Smiles
C1CN (C (=O) CN1C2=C (C (=O) NN=C2) Cl) CC3=CC=CC=C3C (F) (F) F
Molecular Formula
C16H14ClF3N4O2
Additionnal Information
GFB-8438 is a novel, potent, and subtype selective TRP channel subfamily C (TRPC) inhibitor that is equipotent against TRPC4 and TRPC5 with IC50 of 0.18 μM and 0.29 μM, and shows excellent selectivity against TRPC6, other TRP family members , NaV 1.5, as well as limited activity against the hERG channel.
Storage Conditions
3 years -20°C powder
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