PK150
Product Specifications
CAS Number
2165324-62-7
Target
Bacterial
Applications
Microbiology
Smiles
C1=CC2=C (C=C1NC (=O) NC3=CC (=C (C=C3) Cl) C (F) (F) F) OC (O2) (F) F
Molecular Formula
C15H8ClF5N2O3
Additionnal Information
PK150 is an analogue of Sorafenib, which shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 μM, respectively.
Storage Conditions
3 years -20°C powder
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