SB 4
Product Specifications
CAS Number
100874-08-6
Synonyms
BMP signaling agonist sb4, BMPSB4
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
C1=CC=C2C (=C1) N=C (O2) SCC3=CC=C (C=C3) Br
Molecular Formula
C14H10BrNOS
Additionnal Information
SB 4 is a potent and selective agonist of bone morphogenetic protein 4 (BMP4) signaling with EC50 of 74 nM. SB 4 enhances canonical BMP signaling and activates SMAD-1/5/9 phosphorylation. As an agonist of the BMP signaling pathway, SB4 can significantly upregulate the expression levels of classical BMP4 downstream target genes (such as DNA binding inhibitors Id1 and Id3) .
Storage Conditions
3 years -20°C powder
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