NS 1738
Product Specifications
CAS Number
501684-93-1
Synonyms
NSC 213859
Target
AChR
Applications
Neuronal Signaling
Smiles
C1=CC (=C (C=C1C (F) (F) F) NC (=O) NC2=C (C=CC (=C2) Cl) O) Cl
Molecular Formula
C14H9Cl2F3N2O2
Additionnal Information
NS 1738 (NSC 213859) is a novel positive allosteric modulator of the α7 nicotinic acetylcholine receptor (α7 nAChR), with respect to positive modulation of Xenopus laevis oocyte α7 nAChR with EC50 of 3.4 μM, as well as a comparable efficacy at the rat α7 nAChR with EC50 of 3.9 μM.
Storage Conditions
3 years -20°C powder
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