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CBL0137

Product Specifications

CAS Number

1197996-80-7

Synonyms

Curaxin-137, CBL-C137, CBLC137

Target

NF-κB

Applications

NF-κB

Smiles

CC (C) NCCN1C2=C (C=C (C=C2) C (=O) C) C3=C1C=CC (=C3) C (=O) C

Molecular Formula

C21H24N2O2

Additionnal Information

CBL0137 (Curaxin-137) is an inhibitor of the histone chaperone FACT (facilitates chromatin transcription) that simultaneously suppresses NF-κB and activates p53 with EC50 of 0.47 μM and 0.37 μM, respectively.

Storage Conditions

3 years -20°C powder

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