SCH-23390 hydrochloride
Product Specifications
CAS Number
125941-87-9
Synonyms
R- (+) -SCH-23390 hydrochloride, SCH-23390 HCl
Target
Dopamine Receptor
Applications
Neuronal Signaling
Smiles
CN1CCC2=CC (=C (C=C2C (C1) C3=CC=CC=C3) O) Cl.Cl
Molecular Formula
C17H19Cl2NO
Additionnal Information
SCH-23390 hydrochloride (R- (+) -SCH-23390, SCH-23390) is a highly potent and selective dopamine D1-like receptor antagonist with Ki of 0.2 nM and 0.3 nM for the D1 and D5 dopamine receptor subtypes, respectively. SCH-23390 hydrochloride is a potent and high efficacy agonist at h5-HT2C receptors with Ki of 9.3 nM. SCH-23390 hydrochloride directly inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with IC50 of 268 nM.
Storage Conditions
3 years -20°C powder
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