SAR-20347

Product Specifications

CAS Number

1450881-55-6

Target

JAK

Applications

Angiogenesis

Smiles

C1COCCN1C (=O) C2=CC=C (C=C2) NC3=C (N=C (O3) C4=C (C=CC=C4Cl) F) C (=O) N

Molecular Formula

C21H18ClFN4O4

Additionnal Information

SAR-20347 is a potent inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50 of 0.6 nM, 23 nM, 26 nM and 41 nM, respectively. SAR-20347 inhibits TYK2- and JAK1-mediated IL-12 and IFN-α signaling.

Storage Conditions

3 years -20°C powder

More Discoveries

Explore Other Products

Browse additional items from our catalog

EM0732 96 Tests

Mouse Cspg4 (Chondroitin sulfate proteoglycan 4) ELISA Kit

View Details

PV118816 500 ng

RNU6-39 Protein Vector (Human) (pPM-C-HA)

View Details

LV660146 1.0 µg DNA

NAA25 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

View Details

TA503826BM 100 µL

Adiponectin (ADIPOQ) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1H1]

View Details

KWB50210-01 100 mg

2-Methyl-2-[3- (4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl) phenyl]propionitrile

View Details

KWB50210-02 1 g

2-Methyl-2-[3- (4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl) phenyl]propionitrile

View Details