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XCT790

Product Specifications

CAS Number

725247-18-7

Synonyms

Compound 12

Target

Estrogen/progestogen Receptor

Applications

Endocrinology & Hormones

Smiles

COC1=C (C=CC (=C1) C=C (C#N) C (=O) NC2=NN=C (S2) C (F) (F) F) OCC3=C (C=C (C=C3) C (F) (F) F) C (F) (F) F

Molecular Formula

C23H13F9N4O3S

Additionnal Information

XCT-790 (Compound 12) is a potent and selective inverse agonist for estrogen-related receptor α (ERRα) with IC50 of 0.37 μM. XCT-790 (Compound 12) is inactive against ERRγ and the estrogen receptors ERα and ERβ. XCT-790 (Compound 12) significantly inhibits in vivo tumor growth and angiogenesis, and induces apoptosis.

Storage Conditions

3 years -20°C powder

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