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Smurf1-IN-A01

Product Specifications

CAS Number

1007647-73-5

Synonyms

A01, SMURF1 inhibitor A01

Target

E3 Ligase

Applications

Ubiquitin

Smiles

CC1=CC=NN1C2=CC=C (C=C2) C (=O) N3CCN (CC3) S (=O) (=O) C4=CC (=C (C=C4) Cl) C (F) (F) F

Molecular Formula

C22H20ClF3N4O3S

Additionnal Information

Smurf1-IN-A01 can inhibit Smurf1-mediated Smad1/5 degradation and accelerate BMP-2 signal responsiveness with a Kd of 3.664 nM.

Storage Conditions

3 years -20°C powder

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