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MMAF

Product Specifications

CAS Number

745017-94-1

Synonyms

Monomethylauristatin F

Target

Microtubule Associated

Applications

Cytoskeletal Signaling

Smiles

CCC (C) C (C (CC (=O) N1CCCC1C (C (C) C (=O) NC (CC2=CC=CC=C2) C (=O) O) OC) OC) N (C) C (=O) C (C (C) C) NC (=O) C (C (C) C) NC

Molecular Formula

C39H65N5O8

Additionnal Information

MMAF (Monomethylauristatin F) is a synthetic antineoplastic agent and a potent inhibitor of tubulin polymerization. MMAF (Monomethylauristatin F) is applied as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin, ABT-414 and SGN-CD19A.

Storage Conditions

3 years -20°C powder

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