BC-1215
Product Specifications
CAS Number
1507370-20-8
Target
E3 Ligase
Applications
Ubiquitin
Smiles
C1=CC=NC (=C1) C2=CC=C (C=C2) CNCCNCC3=CC=C (C=C3) C4=CC=CC=N4
Molecular Formula
C26H26N4
Additionnal Information
BC-1215 is an inhibitor of F-box protein 3 (Fbxo3, a ubiquitin E3 ligase component) with IC50 of 0.9 μg/mL and LC50 of 87 μg/ml for IL-1β release. BC-1215 inhibits the Fbxo3-TRAF activation pathway by destabilizing TRAF1-6.
Storage Conditions
3 years -20°C powder
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