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COH000

Product Specifications

CAS Number

1534358-79-6

Target

E1 Activating

Applications

Ubiquitin

Smiles

CC1=CC=C (C=C1) CC (C23C=CC (O2) C (=C3C (=O) OC) C (=O) OC) NC4=CC=CC=C4

Molecular Formula

C25H25NO5

Additionnal Information

COH000 is an allosteric, covalent and irreversible ubiquitin-like 1-activating enzyme (SUMO-activating enzyme / E1) inhibitor with IC50 of 0.2 μM for SUMOylation in vitro.

Storage Conditions

3 years -20°C powder

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