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COH-29

Product Specifications

CAS Number

1190932-38-7

Synonyms

RNR Inhibitor COH29

Target

RNR

Applications

DNA Damage/DNA Repair

Smiles

C1=CC=C (C=C1) C2=C (N=C (S2) NC (=O) C3=CC (=C (C=C3) O) O) C4=CC (=C (C=C4) O) O

Molecular Formula

C22H16N2O5S

Additionnal Information

COH29 (RNR Inhibitor COH29) is a potent inhibitor of ribonucleotide reductase (RNR) with anticancer activity. COH29 (RNR Inhibitor COH29) inhibits recombinant RNR small subunit (RRM1/RRM2) activity in vitro with IC50 of 16 μM.

Storage Conditions

3 years -20°C powder

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