Dimethylenastron
Product Specifications
CAS Number
863774-58-7
Synonyms
Eg5 Inhibitor III
Target
HSP (HSP90)
Applications
Cytoskeletal Signaling
Smiles
CC1 (CC2=C (C (NC (=S) N2) C3=CC (=CC=C3) O) C (=O) C1) C
Molecular Formula
C16H18N2O2S
Additionnal Information
Dimethylenastron is a potent, specific and reversible inhibitor of kinesin Eg5 (kinesin-5/kinesin spindle protein, KSP) with IC50 of 200 nM. Dimethylenastron induces mitotic arrest and apoptosis and upregulate Hsp70 in human multiple myeloma cells.
Storage Conditions
3 years -20°C powder
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