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KS176

Product Specifications

CAS Number

1253452-78-6

Target

BCRP

Applications

Transmembrane Transporters

Smiles

C1=CC=C (C (=C1) C (=O) NC2=CC=C (C=C2) CCO) NC (=O) C3=CC=C (C=C3) [N+] (=O) [O-]

Molecular Formula

C22H19N3O5

Additionnal Information

KS176 (compound 9) is a potent and selective inhibitor of the breast cancer resistance protein (BCRP, ABCG2) multidrug transporter with IC50 of 1.39 μM and 0.59 μM in Hoechst 33342 assay and Pheo A assay, respectively.

Storage Conditions

3 years -20°C powder

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