What is the catalog number for MD2-TLR4-IN-1?

The catalog number for MD2-TLR4-IN-1 is C07021-25mg.

What sizes are available for MD2-TLR4-IN-1?

MD2-TLR4-IN-1 is available in the following size(s): 25 mg.

Is MD2-TLR4-IN-1 in stock?

MD2-TLR4-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

MD2-TLR4-IN-1

Product Specifications

CAS Number

2249801-12-3

Target

TLR

Applications

Immunology & Inflammation

Smiles

C1=CC (=C (C (=C1) Cl) C (=O) NC2=CC3=C (C=C2) NN=C3C4=CC5=C (C=C4) NC=C5) Cl

Molecular Formula

C22H14Cl2N4O

Additionnal Information

MD2-TLR4-IN-1 (Compound 22m) is a potent inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) . MD2-TLR4-IN-1 (compound 22m) inhibits lipopolysaccharide (LPS) -induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 of 0.89 μM and 0.53 μM, respectively.