MD2-TLR4-IN-1
Product Specifications
CAS Number
2249801-12-3
Target
TLR
Applications
Immunology & Inflammation
Smiles
C1=CC (=C (C (=C1) Cl) C (=O) NC2=CC3=C (C=C2) NN=C3C4=CC5=C (C=C4) NC=C5) Cl
Molecular Formula
C22H14Cl2N4O
Additionnal Information
MD2-TLR4-IN-1 (Compound 22m) is a potent inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) . MD2-TLR4-IN-1 (compound 22m) inhibits lipopolysaccharide (LPS) -induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 of 0.89 μM and 0.53 μM, respectively.
Storage Conditions
3 years -20°C powder
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